--- title: CrownBio Publications (2) description: (2) --- - English - [简体](http://www.crownbio.cn/) - [日本語](https://crownbio.jp/) [General Contact](https://www.crownbio.com/contact-us) [![crownbio-logo.png](https://info.crownbio.com/hs-fs/hubfs/assets/crownbio-logo.png?width=253&name=crownbio-logo.png "crownbio-logo.png")](https://www.crownbio.com/) [Search](https://info.crownbio.com/publications/page/2#) [![crownbio-logo-xs.png](https://info.crownbio.com/hs-fs/hubfs/assets/crownbio-logo-xs.png?width=413&name=crownbio-logo-xs.png "crownbio-logo-xs.png")](https://www.crownbio.com/) - Site Search 360 - [Call](tel:+18558276968) - [Email](https://www.crownbio.com/contact-us) x ## Publications ![publications-magnifyglass.png](https://info.crownbio.com/hs-fs/hubfs/assets/publications-magnifyglass.png?width=411&name=publications-magnifyglass.png "publications-magnifyglass.png") ## [Renal Disease](https://info.crownbio.com/publications/factsheets/renal-disease/) - Rodent models of renal disease including genetically relevant, translatable, and induced disease models - Genetically relevant models of Polycystic Kidney Disease (PKD) including the *jck* and *pcy* mice and *PCK* rat - The ZDSD polygenic rat model with functional leptin pathway, which develops diabetic... [Read more](https://info.crownbio.com/publications/factsheets/renal-disease/) ## [Obesity](https://info.crownbio.com/publications/factsheets/obesity/) - Rodent models of obesity technologies and resources including our main study endpoints - The FATZO polygenic mouse model with functional leptin pathway for obesity, and metabolic syndrome research - The ZDSD polygenic rat model with functional leptin pathway, a translatable model for obesity research,... [Read more](https://info.crownbio.com/publications/factsheets/obesity/) ## [Diabetes](https://info.crownbio.com/publications/factsheets/diabetes/) - Rodent models of diabetes and our study services including continuous glucose determination - The FATZO polygenic mouse model with functional leptin pathway, a more translatable rodent model for diabetes research - The ZDSD polygenic rat model with functional leptin pathway, a translatable model for... [Read more](https://info.crownbio.com/publications/factsheets/diabetes/) ## [Cardiovascular Disease](https://info.crownbio.com/publications/factsheets/cardiovascular-disease/) - Rodent models of cardiovascular disease technologies and resources including continuous telemetry blood pressure monitoring - The ZDSD polygenic rat model with functional leptin pathway, a highly translatable model which develops hypertension [Read more](https://info.crownbio.com/publications/factsheets/cardiovascular-disease/) ## [Isotype Control Antibodies](https://info.crownbio.com/publications/application-notes/isotype-control-antibodies/) CrownBio has developed a full suite of IgG isotype controls specifically for use in *in vivo* animal studies and high throughput screening assays. Read more on immunogen selection, antibody analysis and purity, as well as *in vivo* testing. [Read more](https://info.crownbio.com/publications/application-notes/isotype-control-antibodies/) ## [Translational Oncology](https://info.crownbio.com/publications/application-notes/translational-oncology/) Find out how our fully integrated Translational Oncology Platform de-risks transitioning your therapy into the clinic, from PDX selection to discovery of biomarkers and gene signatures for patient stratification. [Read more](https://info.crownbio.com/publications/application-notes/translational-oncology/) ## [Triple Negative Breast Cancer (TNBC)](https://info.crownbio.com/publications/application-notes/triple-negative-breast-cancer/) CrownBio details our range of TNBC research platforms (including a collection of nearly 20 PDX models) for this high unmet need disease area. [Read more](https://info.crownbio.com/publications/application-notes/triple-negative-breast-cancer/) ## [Studylog](https://info.crownbio.com/publications/application-notes/publication/studylog/) Find out why Studylog® is the best animal study workflow suite for efficiently running multiple, large, multicenter HuTrials. [Read more](https://info.crownbio.com/publications/application-notes/publication/studylog/) ## [Small Cell Lung Cancer (SCLC)](https://info.crownbio.com/publications/application-notes/small-cell-lung-cancer/) Focusing on our collection of around 70 SCLC PDX models, we present full model characterization, validation, and *in vivo* pharmacology, as well as a novel SCLC HuTrial case study. [Read more](https://info.crownbio.com/publications/application-notes/small-cell-lung-cancer/) ## [Prostate Cancer](https://info.crownbio.com/publications/application-notes/prostate-cancer/) Investigate our fully comprehensive suite of prostate cancer platforms, including the development of hard-to-build PDX models. [Read more](https://info.crownbio.com/publications/application-notes/prostate-cancer/) - [Older Posts](https://info.crownbio.com/publications/page/3) - [Newer Posts](https://info.crownbio.com/publications/page/1) ### Corporate - [About Us](https://www.crownbio.com/about/company/) - [Careers](https://www.crownbio.com/about/careers/) - [Investors - Investor relations](https://www.crownbio.com/about/investors/) - [Leadership Team](https://www.crownbio.com/leadership-team) - [About JSR Life Sciences](https://www.crownbio.com/about/jsr-life-science) - [Scientific Advisors](https://www.crownbio.com/about/scientific-advisors/) - [Strategic Partners](https://www.crownbio.com/about/strategic-partners/) - [Mission & Vision](https://www.crownbio.com/about/vision-and-mission/) - [What we do](https://www.crownbio.com/about/what-we-do) - [News](https://blog.crownbio.com/press) - [Resources](https://www.crownbio.com/resources) - [Blog](https://blog.crownbio.com/) ### Models - [Cell Line Derived Xenograft](https://www.crownbio.com/oncology/in-vivo-services/cell-line-derived-cdx-tumor-models) - 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[Radiation Therapy](https://www.crownbio.com/oncology/in-vivo-services/radiation-therapy) - [Syngeneic Tumor Models](https://www.crownbio.com/oncology/in-vivo-services/syngeneic-tumor-models) **[*In Vitro* Services](https://www.crownbio.com/oncology/in-vitro-services)** - [Cell Based Screening](https://www.crownbio.com/oncology/in-vitro-services/cell-based-screening) - [CrownSyn](https://www.crownbio.com/oncology/crownsyn) - [Cell Line and Model Authentication](https://www.crownbio.com/oncology/cell-line-and-model-authentication) - [Cell Line Panels](https://www.crownbio.com/oncology/in-vitro-services/cell-line-panels/) - [Flow Cytometry Platform](https://www.crownbio.com/oncology/in-vitro-services/facs-platform) - [Immuno-Oncology](https://www.crownbio.com/oncology/in-vitro-services/immuno-oncology) - [OmniScreen Cell Based Screening Service](https://www.crownbio.com/oncology/in-vitro-services/omniscreen-cell-based-screening-service/) - [PDX-Derived Cell Lines](https://www.crownbio.com/oncology/in-vitro-services/pdx-derived-cell-lines/) **[Organoids](https://www.crownbio.com/oncology/hub-organoids/hub-organoids-for-drug-discovery)** - [Cell Line and Model Authentication](https://www.crownbio.com/oncology/cell-line-and-model-authentication) - [Organoid and Immune Cell Co-Culture](https://www.crownbio.com/oncology/hub-organoids/organoid-and-immune-cell-co-culture) **[*Ex Vivo* Services ](https://www.crownbio.com/oncology/ex-vivo-services)** - [3D Assays](https://www.crownbio.com/oncology/ex-vivo-services/3d-assays/) - [Tumor Microarrays](https://www.crownbio.com/oncology/ex-vivo-services/tumor-microarrays) **[High Content Imaging ](https://www.crownbio.com/oncology/high-content-imaging)** - [3D *Ex Vivo* Patient Tissue Platform](https://www.crownbio.com/3d-ex-vivo-patient-tissue-platform) **[Immuno-Oncology](https://www.crownbio.com/oncology/immuno-oncology-preclinical-models)** - [CAR-T Cell Therapy Models](https://www.crownbio.com/oncology/immuno-oncology/car-t-cell-therapy-models/) - [Humanized Models](https://www.crownbio.com/oncology/immuno-oncology/humanized-mouse-models/) - [Hematopoietic Stem Cell (HSC)-PDX](https://www.crownbio.com/oncology/immuno-oncology/hematopoietic-stem-cell-hsc-pdx) - [MiXeno](https://www.crownbio.com/oncology/immuno-oncology/mixeno) - [Human Target Knock-In Models](https://www.crownbio.com/oncology/immuno-oncology/human-target-knock-in-models) - [HuGEMM](https://www.crownbio.com/oncology/immuno-oncology/hugemm) - [HuCELL](https://www.crownbio.com/oncology/immuno-oncology/hucell) - [Murine Immunity Model and Services](https://www.crownbio.com/oncology/immuno-oncology/murine-efficacy-pd-models/) - [Tumor Homograft](https://www.crownbio.com/oncology/immuno-oncology/murine-efficacy-pd-models/mouse-tumor-models/) - [Syngeneic tumor](https://www.crownbio.com/oncology/in-vivo-services/syngeneic-tumor-models) - [MuScreen](https://www.crownbio.com/oncology/immuno-oncology/muscreen) - [Mouse I/O RNA-Seq Panel](https://www.crownbio.com/oncology/biomarker-assay-services/genomics-services/mouse-io-rna-seq-panel) ### Oncology **[Biomarker Discovery and CDx](https://www.crownbio.com/biomarker-discovery-companion-diagnostics/)** - [Biomarkers of Response (HuMark)](https://www.crownbio.com/oncology/translational-oncology/biomarkers-of-response) - [Mouse Clinical Trials (HuTrial)](https://www.crownbio.com/oncology/translational-oncology/biomarkers-of-response) - [Signatures of Response (HuSignature)](https://www.crownbio.com/oncology/translational-oncology/signatures-of-response) **[Biomarker Assay Services](https://www.crownbio.com/oncology/biomarker-assay-services)** - [Clinical Chemistry and Biomarkers](https://www.crownbio.com/reliable-clinical-chemistry-biomarker-services) - [Cytokine and Chemokine Profiling](https://www.crownbio.com/oncology/biomarker-assay-services/cytokine-and-chemokine-profiling#_) - [Flow Cytometry](https://www.crownbio.com/oncology/in-vitro-services/facs-platform) - [Genomics Services](https://www.crownbio.com/oncology/biomarker-assay-services/genomics-services) - [Mouse I/O RNA-Seq Panel](https://www.crownbio.com/oncology/biomarker-assay-services/genomics-services/mouse-io-rna-seq-panel) - [Histology and Digital Pathology](https://www.crownbio.com/oncology/biomarker-assay-services/histology-and-digital-pathology) - [Rare Cell Analysis](https://www.crownbio.com/biomarker-assay-services/rare-cell-analysis) **[Bioinformatics](https://www.crownbio.com/oncology/bioinformatics)** - [CrownSyn](https://www.crownbio.com/oncology/crownsyn) **[Pharmacology and Bioanalytical Services](https://www.crownbio.com/oncology/pharmacology-and-bioanalytical-services/)** - [DMPK Services](https://www.crownbio.com/oncology/pharmacology-and-bioanalytical-services/dmpk-services) - [Rodent Immuno-Safety Models](https://www.crownbio.com/oncology/pharmacology-and-bioanalytical-services/rodent-immuno-safety-models) - [Rodent Safety Pharmacology](https://www.crownbio.com/metabolic-disease/safety-toxicology/rodent-models/) - [Structural Biology](https://www.crownbio.com/oncology/pharmacology-and-bioanalytical-services/protein-sciences/) - [Target Validation](https://www.crownbio.com/oncology/in-vivo-services/target-validation) **[Oncology Databases](https://www.crownbio.com/oncology/oncology-databases)** - [HuBase](https://www.crownbio.com/hb-registration) - [OrganoidBase](https://www.crownbio.com/ob-registration) - [MuBase](https://www.crownbio.com/mb-registration) - [Onco*Express*](https://www.crownbio.com/oncoexpress-registration) - [XenoBase](https://www.crownbio.com/xb-registration) ### Follow Us [![](https://info.crownbio.com/hubfs/assets/soc-fb.png)](https://www.facebook.com/crownbio/)[![](https://info.crownbio.com/hubfs/assets/soc-tw.png)](https://twitter.com/crownbioscience)[![](https://info.crownbio.com/hubfs/assets/soc-in.png)](https://www.linkedin.com/company/693709/) ![](https://info.crownbio.com/hs-fs/hubfs/assets/jsr-logo2.png?width=200&name=jsr-logo2.png) - © Crown Bioscience Inc.    ![](https://info.crownbio.com/hs-fs/hubfs/assets/jsr-logo2.png?width=200&name=jsr-logo2.png) - [Contact Us](https://www.crownbio.com/contact-us) - [Site Map](https://www.crownbio.com/sitemap.xml) - [Terms of Use](https://www.crownbio.com/terms-of-use/) - [Privacy Policy](https://www.crownbio.com/privacy-policy/) - © 2019 Crown Bioscience Inc. ![](https://secure.leadforensics.com/142048.png)