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Publications

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  • Rodent models of renal disease including genetically relevant, translatable, and induced disease models
  • Genetically relevant models of Polycystic Kidney Disease (PKD) including the jck and pcy mice and PCK rat
  • The ZDSD polygenic rat model with functional leptin pathway, which develops diabetic...

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  • Rodent models of obesity technologies and resources including our main study endpoints
  • The FATZO polygenic mouse model with functional leptin pathway for obesity, and metabolic syndrome research
  • The ZDSD polygenic rat model with functional leptin pathway, a translatable model for obesity research,...

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  • Rodent models of diabetes and our study services including continuous glucose determination
  • The FATZO polygenic mouse model with functional leptin pathway, a more translatable rodent model for diabetes research
  • The ZDSD polygenic rat model with functional leptin pathway, a translatable model for...

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  • Rodent models of cardiovascular disease technologies and resources including continuous telemetry blood pressure monitoring
  • The ZDSD polygenic rat model with functional leptin pathway, a highly translatable model which develops hypertension

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CrownBio has developed a full suite of IgG isotype controls specifically for use in in vivo animal studies and high throughput screening assays. Read more on immunogen selection, antibody analysis and purity, as well as in vivo testing.

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Find out how our fully integrated Translational Oncology Platform de-risks transitioning your therapy into the clinic, from PDX selection to discovery of biomarkers and gene signatures for patient stratification.

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CrownBio details our range of TNBC research platforms (including a collection of nearly 20 PDX models) for this high unmet need disease area.

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Find out why Studylog® is the best animal study workflow suite for efficiently running multiple, large, multicenter HuTrials.

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Focusing on our collection of around 70 SCLC PDX models, we present full model characterization, validation, and in vivo pharmacology, as well as a novel SCLC HuTrial case study.

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Investigate our fully comprehensive suite of prostate cancer platforms, including the development of hard-to-build PDX models.

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